Physchem.cz

This dissertation focuses on the design and synthesis of advanced stimuli-responsive polymers for biomedical applications, including polymer therapeutics and medical devices. By leveraging modern polymerization techniques (e.g., controlled radical polymerizations such as ATRP and RAFT) and exploring poly(2-oxazoline) systems, we aim to achieve precise control over polymer structure and function. The resulting polymers will exhibit tunable properties in response to changes in the environment (e.g., pH, temperature, or specific biochemical stimuli), thus enabling targeted drug delivery, enhanced biocompatibility, and improved therapeutic performance. This research provides a versatile platform for the development of next-generation biomaterials and offers promising directions for personalized medicine and other emerging fields in healthcare.