The Soft Matter Theory Group, headed by professor Filip Uhlík, is a part of the Department of Physical and Macromolecular Chemistry of the Charles University in Prague. Our interdisciplinary research very much sits at the interface between physics and chemistry of macromolecules and biomacromolecules. It includes study of solutions of both synthetic and biological macromolecules; their thermodynamic and kinetic properties, such as self assembly, aggregation, diffusion, etc.

If you are interested in joining our group, as a graduate or undergraduate student, or as a postdoctoral fellow, please see the student topics section.


  • Mean field analytiacal and numerical modelling
  • Langevin dynamics
  • Hybrid Monte-Carlo
  • Hartree–Fock 
  • Density functional methods

People of the group

Filip Uhlík

Doc. RNDr., Ph.D.

Deputy head, associate professor

Lucie Nová

Ing., Ph.D.

Assistant professor

Oleg Rud



Peter Illés


Master student

Matěj Lang

Bachelor student

Iryna Morozova

Bachelor student

Research topics

Coarse-grained protein models

19 Jul 2021

  • coarse-grained protein models

Simulations of polyelectrolytes

28 May 2019

  • polyelectrolyte solutions and gels
  • linear and branched polyelectrolytes
  • star-like, comb-like architectures
  • polyelectrolyte gels (infinite networks)
  • dissociation of weak polyelectrolytes and polyampholytes

Mean field modelling of polymers

28 May 2019

  • Scheutjenes-Fleer Self-Consistent Field Theory (SF-SCF)
  • Hybrid SCF - Monte Carlo modelling

Quantum chemistry

28 May 2019

  • Endohedral fullerenes
  • Quantum Monte Carlo simulations

Research topics for students

Selected Publications

of Soft Matter group

Z. Slanina, F. Uhlík, L. Feng, T. Akasaka, X. Lu, and L. Adamowicz,
Calculations of the Lu3N@C80 two-isomer equilibrium
Fullerenes, Nanotubes and Carbon Nanostructures, 27(5), 2019