The Soft Matter Theory Group, headed by professor Filip Uhlík, is a part of the Department of Physical and Macromolecular Chemistry of the Charles University in Prague. Our interdisciplinary research very much sits at the interface between physics and chemistry of macromolecules and biomacromolecules. It includes study of solutions of both synthetic and biological macromolecules; their thermodynamic and kinetic properties, such as self assembly, aggregation, diffusion, etc.
If you are interested in joining our group, as a graduate or undergraduate student, or as a postdoctoral fellow, please see the student topics section.
We study the behavior of polyelectrolyte solutions and gels, including linear, branched, star-like, and comb-like architectures. Our focus includes infinite gel networks, dissociation in weak polyelectrolytes, and polyampholytes, providing insights ...
Metallo-polyelectrolyte complexes (MPECs) are physical gels formed by the interaction of long polyelectrolyte chains with multivalent metal ions (e.g., Ca2+, Al3+). These gels exhibit self-healing properties, making ...
Fullerenes can encapsulate atoms as qubits for quantum computing. AI-trained potentials, based on ab initio data, enable efficient and accurate long-term simulations of these systems, advancing quantum technology.
We use coarse-grained (CG) models to study protein dynamics efficiently. By applying Boltzmann inversion, we derive interaction potentials from atomistic data, preserving key structural features. These models help explore protein ...
We study hydrogels, coacervates, nanoparticles, and polymer brushes using large-timescale simulations. By combining Scheutjens-Fleer Self-Consistent Field Theory and hybrid SCF-Monte Carlo modeling, we explore their structure, dynamics, and material properties ...
Our research employs quantum chemistry and Quantum Monte Carlo (QMC) simulations to investigate electronic structures and properties of molecular systems with high accuracy. QMC methods enable us to explore complex ...
