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The minimal membrane requirements for BAX-induced pore opening upon exposure to oxidative stress

Biophysical Journal, 2024

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V. Obsilova, and T. Obsil,
Look for the Scaffold: Multifaceted Regulation of Enzyme Activity by 14-3-3 Proteins

BibTeX

V. Obsilova, and T. Obsil,
The yeast 14-3-3 proteins Bmh1 and Bmh2 regulate key signaling pathways

DOI, BibTeX

K. Honzejkova, D. Kosek, V. Obsilova, and T. Obsil,
The cryo-EM structure of ASK1 reveals an asymmetric architecture allosterically modulated by TRX1

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B. A. Somsen E. Sijbesma S. Leysen K. Honzejkova E. J. Visser P. J. Cossar T. Obsil L. Brunsveld et al.
Molecular basis and dual ligand regulation of tetrameric estrogen receptor α/14-3-3ζ protein complex

Journal of Biological Chemistry, 299(7), 2023

nuclear receptors protein–protein interactions estrogen receptor 14-3-3 protein ppi stabilization

DOI, BibTeX

V. Obsilova, and T. Obsil,
Structural insights into the functional roles of 14-3-3 proteins

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K. Kohoutova V. Docekal M. J. Ausserlechner N. Kaiser A. Tekel R. Mandal M. Horvath V. Obsilova et al.
Lengthening the Guanidine–Aryl Linker of Phenylpyrimidinylguanidines Increases Their Potency as Inhibitors of FOXO3-Induced Gene Transcription

ACS Omega, 7(38), 2022

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R. Mandal, K. Kohoutova, O. Petrvalska, M. Horvath, P. Srb, V. Veverka, V. Obsilova, and T. Obsil,
FOXO4 interacts with p53 TAD and CRD and inhibits its binding to DNA

DOI, BibTeX

R. Joshi, P. Pohl, D. Strachotova, P. Herman, T. Obsil, and V. Obsilova,
Nedd4-2 binding to 14-3-3 modulates the accessibility of its catalytic site and WW domains

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M. Horvath, O. Petrvalska, P. Herman, V. Obsilova, and T. Obsil,
14-3-3 proteins inactivate DAPK2 by promoting its dimerization and protecting key regulatory phosphosites

DOI, BibTeX

V. Obsilova, K. Honzejkova, and T. Obsil,
Structural Insights Support Targeting ASK1 Kinase for Therapeutic Interventions

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S. Leysen R. J. Burnley E. Rodriguez L.-G. Milroy L. Soini C. J. Adamski L. Nitschke R. Davis et al.
A Structural Study of the Cytoplasmic Chaperone Effect of 14-3-3 Proteins on Ataxin-1

Journal of Molecular Biology, 433(19), 2021

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Neves J.F. Petrvalská O. Bosica F. Cantrelle F.-X. et al.
Phosphorylated full-length Tau interacts with 14-3-3 proteins via two short phosphorylated sequences, each occupying a binding groove of 14-3-3 dimer

FEBS Journal, 288, 1918-1934, 2021

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P. Pohl, R. Joshi, O. Petrvalska, T. Obsil, and Obsilova V,
14-3-3-protein regulates Nedd4-2 by modulating interactions between HECT and WW domains

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D. Kalabova, F. Filandr, M. Alblova, O. Petrvalska, M. Horvath, P. Man, T. Obsil, and V. Obsilova,
14-3-3 protein binding blocks the dimerization interface of caspase-2

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M. Wolter, D. L. Santo, P. Herman, A. Ballone, F. Centorrino, T. Obsil, and C. Ottmann,
Interaction of an IpkappaBpalpha Peptide with 14-3-3

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D. L. Santo, O. Petrvalska, V. Obsilova, C. Ottmann, and T. Obsil,
Stabilization of Protein\textendashProtein Interactions between CaMKK2 and 14\textendash3\textendash3 by Fusicoccins

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V. Obsilova, and T. Obsil,
The 14-3-3 Proteins as Important Allosteric Regulators of Protein Kinases

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J. Hagenbuchner V. Obsilova T. Kaserer N. Kaiser B. Rass K. Psenakova V. Docekal M. Alblova et al.
Modulating FOXO3 transcriptional activity by small, DBD-binding molecules

eLife, 8, e48876, 2020

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